Oocytes vitrification

Treatments

To improve your chances of pregnancy in the future

Oocytevitrification (or oocyte freezing) is apreservation fertilitytreatment based onthe ultrarapid freezingof eggs obtained after an ovarian stimulation.

It is indicated in:

1. Couples that don’t want to freeze surplus embryos from an IVF cycle.
2. Women who desire to postpone their maternity.
3.Before a chemotherapy or radiotherapy treatment De esta manera se transfieren los embriones que consiguen (1 ó 2) y no hay embriones sobrantes para congelar.

The ideal age for the vitrification of eggs is before 30, although results are good until 35 and more limited between 36 and 39. This treatment does not change the age of menopause After 40, oocyte preservation is not recommended. Women are born with a genetically determined number of eggs and at age 35, only 10% of the ovarian reserve remains. A decrease in the number of ovules, se le suma el empeoramiento de la calidad ovocitaria, lo que se traduce en conseguir menos embarazos y aumentar el riesgo de aborto y anomalías en los niños nacidos. Freezing eggs, if the woman opts for late motherhood, will reduce the riskof needing donor eggs for that purpose.

The ideal age for the vitrification of eggs is before 30, althoughresults are good until 35 andmore limited between 36 and 39. After 40, oocyte preservation is not recommended. This treatment does not change the age of menopause

Para conocer el precio de la congelación de óvulos consulta elPlan Concibe.

Oocyte vitrification consists of:

1.Ovarian stimulation: is carried out after menstruationwith injectable hormonal preparations(subcutaneous). This treatment is controlled with serial transvaginal ultrasound and blood tests during 6-8 days with the aim of achieving a good

2.Recovery of oocytes: The oocytes are collected bypiercing the ovaries through the vagina, under ultrasound control, and aspiratingthe content of the follicles

(small sacks of liquid each containing an oocyte). The follicular puncture is practiced under sedation in the operating theater, and lasts from 10 to 15 minutes. Afew hours laterthe patient returns home, where she rests throughout the whole day.

2.Recovery of oocytes: The oocytes are collected bypiercing theovaries through the vagina, under ultrasound control, and aspiratingthe content of the follicles The follicular puncture is practicedunder sedation in the operating theater, and lasts from 10 to 15 minutes. A few hours later the patient returns home, where she rests throughout the whole day.

3. Vitrificación ovocitaria: En el laboratorio, el mismo día de la punción ovárica, los ovocitos son tratados con sustancias crioprotectoras y sumergidos en nitrógeno líquido a una temperatura de -196ºC.

After oocyte retrieval, no more medication is needed , and themenstruation will come in 3 to 10 days. The duration of treatment is 10 to 15 days and the patient can lead a normal lifeduring the treatment.

The optimun number of frozen oocytes, to have a future pregnancy rate around 100%, is 20 to 30, depending on the woman´s age. In one ovarian stimulation cycle we obtain between 10 to 20 oocytes in women with a normal ovarian reserve, and 6 to 10 in women above 35.

How to get a future pregnancy with frozen eggs

When the patient decides to use the vitrified oocytes, they will be devitrified (or thawed). The oocytes will be inseminated through in vitro fertilization with ICSI or microinjection of a sperm from the partner (or donor sperm) into each egg. Thus, the next day, we will have embryos that can be transferred to the uterus.

Embryo transfer can be performed in a natural cycle, without stimulation of the ovaries. This consists of performing 2 or 3 ovulation monitoring ultrasounds; and 5 days after ovulation, 1 or 2 embryos are transferred to the woman’s uterus. Ten days later, we will know if the pregnancy has been achieved. The probability of pregnancy by embryo transfer is 67%in women under 31 years of age. Es normal necesitar hasta 3 embriones para conseguir un embarazo.

For more information on prices of oocyte vitrification you can visit our Concibe plan page.

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