The FISH(Fluorescence in situ hybridization) test is an analysis used to detect possible alterations in sperm chromosomes. This test is indicated in the case of altered spermiogramor male karyotype, in repetitive miscarriages, or in implantation failures.
During the formation of the spermatozoa in the testes, errors can occur thatwill giveriseto sperm with an extra copyof achromosome (disomy), withoutachromosome (monosomy)or with all chromosomes duplicated(diploidy). If any of these abnormal spermatozoa, fertilize the oocyte, the result could be the non-implantation of the resulting embryo or miscarriages. The number of chromosomes to be studied (3, 4, 5 or 9 chromosomes), the number of counted spermatozoa (from a few hundred to thousands) and its realization in an automated (computer) or manual (by an operator) way,determines the reliability and quality of the result.
In URH García del Real, we collaborate with an external genetics laboratory with wide experience in this technique (Genomic Systems).We analyze the largest number of chromosomes (9) possible, through an automated system that looks at 10,000 sperm. We, thus, obtain reliable and reproducible results, in the shortest possible time. This test is performed on a semen sample obtained by masturbation.
This test is performed on asemen sampleobtained by masturbation. and there is a specific room for obtaining this type of samples. Debe tener una abstinencia sexual de 3 a 5 días antes de realizar la prueba. It is necessary to ask for an appointment directly with the staff of the IVF Laboratory. The test can be performed from Monday to Friday from8 a.m. to 4 p.m. Results are available in 2-3 working days. The results will beavailable in 3-4 weeks.